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KMID : 0363220130510070548
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Korean Journal of Dermatology
2013 Volume.51 No. 7 p.548 ~ p.551
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A Case of Clear Cell Basal Cell Carcinoma
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Kwon Sun-Yong
Park Sang-Hyun
Kim Ui-Kyung
Park Kun
Park Seok-Don
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Abstract
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Clear cell basal cell carcinoma is a rare histological variant of basal cell carcinoma, which is characterized by a variable component of clear cells. We report a case of clear cell basal cell carcinoma in a 53-year-old Caucasian male presented with a red 0.7×0.6 cm sized nodule with central bleeding on left cheek for 2 years. Histological examinations showed multiple dermal tumor lobules nested with basaloid cells of a peripheral palisading pattern. In addition, prominent clear cell changes were observed in the center of large nests. The clear cells showed a single large vacuole in their eosinophilic and granular cytoplasm with eccentric condensed nucleus. The clear tumor cells was stained with periodic acid Schiff and showed incomplete diastase-resistance. Intercellular mucin staining with alcian blue was positive. The tumor was successfully treated with Mohs micrographic surgery and no recurrence has been observed for 6 months.
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KEYWORD
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Basal cell carcinoma, Clear cell
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